Table 2 |
||||
|
NNS use during the first 21 full days of treatment; data from 1050 days of observation from 50 patients.* |
||||
|
NNS 1 dose per hour |
NNS Ad libitum |
Wald Chi2 test |
ICC‡ |
|
|
Mean (CI 95%) |
Mean (CI 95%) |
p-value |
ρ |
|
|
|
||||
|
Doses |
||||
|
Daily number of intakes |
13.6 (4.7; 22.6) |
11.1 (7.3; 14.8) |
p = 0.332 |
ρ = 0.606 |
|
Daily number of correct doses (2 puffs) |
12.0 (3.9; 20.2) |
9.3 (5.9; 12.7) |
p = 0.263 |
ρ = 0.593 |
|
Daily number of single puff |
0.5 (-0.4; 1.5) |
0.8 (0.4; 1.2) |
p = 0.470 |
ρ = 0.414 |
|
Daily number of doses over 2 puffs |
1.1 (-0.1; 2.2) |
1.0 (0.5;1.4) |
p = 0.780 |
ρ = 0.331 |
|
Period of use |
||||
|
Daily intake 1st week |
13.7 (3.6; 23.8) |
12.9 (8.7; 17.1) |
p = 0.788 |
ρ = 0.798 |
|
Daily intake 2nd week |
14.5 (4.4;24.6) |
10.5 (6.3; 14.7) |
p = 0.184 |
ρ = 0.696 |
|
Daily intake 3rd week |
12.8 (5.6; 22.2) |
9.8 (5.8;13.7) |
p = 0.287 |
ρ = 0.656 |
|
Week days |
||||
|
Daily intake weekends |
13.2 (4.3; 22.2) |
9.7 (6.0;13.4) |
p = 0.189 |
ρ = 0.525 |
|
Daily intake weekdays |
13.8 (4.5; 23.1) |
11.6 (7.7; 15.4) |
p = 0.419 |
ρ = 0.652 |
|
Use of NNS |
||||
|
Days NNS was used† |
22.9 (19.0; 27.3) |
23.0 (18.8;27.3) |
p = 0.966 |
- |
|
Total nicotine (mg)† |
418 (294; 543) |
296 (188; 405) |
p = 0.131 |
- |
|
|
||||
|
* Results are drawn from random-effect GLS regression taking lack of independence from measurements from the same patients into consideration. † Individual level data was used for this analysis. T-test was used to calculate p-value. ‡ The Intraclass Correlation Coefficient (ρ) corresponds to the percentage of variance due to individual characteristics (cluster level). |
||||
|
Rey et al. Substance Abuse Treatment, Prevention, and Policy 2009 4:12 doi:10.1186/1747-597X-4-12 |
||||
